Endometrial effects of long-term treatment with phytoestrogens

Objective: To determine the effects of 5 years of treatment with soy phytoestrogens on histological characteristics of endometrium in postmenopausal women.

Design: Randomized, double-blind, placebo-controlled study.

Setting: Centre of Perinatal and Reproductive Medicine, Department of Gynecological, Obstetrical, and Pediatric Sciences, University of Perugia, Italy.

Patient(s): Three hundred seventy-six postmenopausal healthy …