Psychological assessment of the effects of treatment with phytoestrogens on postmenopausal women: a randomized, double-blind, crossover, placebo-controlled study

Objective: To investigate the effects of soy isoflavones on mood and cognitive function in postmenopausal women.

Design: Randomized, double-blind, cross-over, placebo-controlled trial.

Setting: University Hospital, Milan, Italy; A.G.UN.CO. Obstetrics and Gynaecology Centre, Rome, Italy.

Patient(s): Seventy-eight postmenopausal women. Intervention(s): We administered 60 mg/day isoflavones or placebo for 6 months. After a washout period of 1 month, the patients …