Use of ethinyl estradiol to reverse the antiestrogenic effects of clomiphene citrate in patients undergoing intrauterine insemination

Objective: To compare the effectiveness of clomiphene citrate used alone and in combination with ethinyl E2 for the induction of ovulation in patients undergoing IUI.

Design: Randomized, double-blind study. Setting: Four infertility treatment centers. Patient(s): Women aged 25–35 years with infertility of at least 2 years’ duration and oligomenorrhea or amenorrhea associated with a positive menstrual …