Psychological assessment of the effects of treatment with phytoestrogens on postmenopausal women: a randomized, double-blind, crossover, placebo-controlled study

Objective: To investigate the effects of soy isoflavones on mood and cognitive function in postmenopausal women.

Design: Randomized, double-blind, cross-over, placebo-controlled trial.

Setting: University Hospital, Milan, Italy; A.G.UN.CO. Obstetrics and Gynaecology Centre, Rome, Italy.

Patient(s): Seventy-eight postmenopausal women. Intervention(s): We administered 60 mg/day isoflavones or placebo for 6 months. After a washout period of 1 month, the patients …


Phytoestrogens may improve the pregnancy rate in in vitro fertilization– embryo transfer cycles

Objective: To compare the effectiveness of IM P and IM P plus oral phytoestrogens for luteal phase support in patients undergoing IVF-ET cycles.

Design: Prospective, controlled, randomized trial. Setting: University Hospital, Perugia, Italy.

Patient(s): Two hundred thirteen infertile patients undergoing IVF-ET were included in the study. The inclusion criteria were use …


Endometrial effects of long-term treatment with phytoestrogens

Objective: To determine the effects of 5 years of treatment with soy phytoestrogens on histological characteristics of endometrium in postmenopausal women.

Design: Randomized, double-blind, placebo-controlled study.

Setting: Centre of Perinatal and Reproductive Medicine, Department of Gynecological, Obstetrical, and Pediatric Sciences, University of Perugia, Italy.

Patient(s): Three hundred seventy-six postmenopausal healthy …