High dose of phytoestrogens can reverse the antiestrogenic effects of clomiphene citrate on the endometrium
OBJECTIVE: To compare the effectiveness of clomiphene citrate (CC) alone or combined with phytoestrogens (PE) in ovulation induction in patients who had intrauterine insemination in a randomized, double-blind study. METHODS: A total of 134 women aged 25-35 years, who were infertilefor at least 2 years and who had oligomenorrhea or amenorrhea associated with a positive […]
Endometrial effects of long-term treatment with phytoestrogens
Objective: To determine the effects of 5 years of treatment with soy phytoestrogens on histological characteristics of endometrium in postmenopausal women. Design: Randomized, double-blind, placebo-controlled study. Setting: Centre of Perinatal and Reproductive Medicine, Department of Gynecological, Obstetrical, and Pediatric Sciences, University of Perugia, Italy. Patient(s): Three hundred seventy-six postmenopausal healthy women, all with intact uterus. […]